Whicker reported stories of social interest from around the world. His interviewees included locals, politicians, celebrities, and even convicted criminals as he reported on stories as far ranging as military dictatorships, British expatriates, the feminist movement of the 1970s, the Tanka people of Hong Kong, the American Gay Rights movement, the building of Disneyworld in Florida, and the plastic surgery industry. Among his interviewees were actors Peter Sellers, Joan Collins, Britt Ekland, Liza Minnelli, and Christopher Lee, Haitian dictator François "Papa Doc" Duvalier, Paraguayan dictator Don Alfredo Stroessner, novelist Harold Robbins, Lula Parker Betenson (the 94-year-old sister of the outlaw Butch Cassidy), the Sultan of Brunei Hassanal Bolkiah (reputedly the richest man in the world at the time of filming), opera singer Luciano Pavarotti, several former Maharajas of India, and various members of the British aristocracy.
Although episodes were self-contained, Whicker would often film a series of episodes devoted to one particular location or subject, including five whole series devoted to the United States and three about Australia. Multi-episode series dedicated to the South Pacific, Europe, India, Hong Kong, Spain, and a voyage on the QE2 were also made. These were usually given series titles such as Whicker's New World (1969), Whicker In Europe(1970), Whicker's Walkabout: Seven Scenes Down Under (1970), Whicker Within A Woman's World (1972), Whicker Way Out West (1973), Whicker's South Seas (1973), Whicker's World Down Under (1976), Whicker's World: A Fast Boat to China (1984), Whicker's World: Living With Uncle Sam (1985), Whicker's World: Living with Waltzing Maltilda (1988), and Whicker's World: A Taste of Spain (1992). Two episodes were filmed on theOrient Express, the first on the Venice-Simplon Orient Express in 1982 and the second on the Eastern and Oriental Express in 1993.