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SUMO Regulation of Cellular Processes by Van G. Wilson (Paperback, 2014)

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Product Information

Over a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small Ubiquitin-like Modifier, or SUMO. Sumoylation is a post-translational modification that utilizes SUMO as the modifier group covalently attached to target substrates. This state-of-the art review on the sumoylation system deals with protein modification as it pertains to regulation of diverse cellular functions. Each chapter has been written by a leading researcher and covers the role of sumoylation in fundamental biochemical activities (transcription, RNA processing, chromatin remodelling, DNA repair, nucleocytoplasmic transport, ion channel regulation, and metabolic pathways). The text also examines the part sumoylation plays in critical cellular processes such as mitosis, meiosis, differentiation, senescence, and apoptosis. Lastly, the emerging role of sumoylation in specific diseases, including cancer and diabetes as well as neurodegenerative ones, is explored with an emphasis on defining molecular mechanisms that may provide new targets for treatment or prevention. While SUMO was discovered more than 10 years ago, this is still a relatively young field, and much remains to be discovered about the biochemical and biological properties of this modification system. In just the last few years, it has become clear that sumoylation modifies hundreds of cellular proteins, and there has been increased appreciation for the breadth of cellular functions that are impacted by this post-translational modification.

Product Identifiers

Publisher
Springer
ISBN-13
9789400791442
eBay Product ID (ePID)
209676773

Product Key Features

Author
Van G. Wilson
Publication Name
Sumo Regulation of Cellular Processes
Format
Paperback
Language
English
Subject
Medicine, Chemistry, Biology
Publication Year
2014
Type
Textbook
Number of Pages
339 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Item Weight
539g

Additional Product Features

Editor
Van G. Wilson
Country/Region of Manufacture
Netherlands

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SUMO Regulation of Cellular Processes by Van G. Wilson (Paperback, 2014)

Best-selling in Adult Learning & University

Secrets Of Mental Math: The Mathemagician's Guide to Lightening Calculation and Amazing Maths Tricks by Arthur Benjamin, Michael Shermer (Paperback, 2006)

Never Split the Difference: Negotiating as if Your Life Depended on It by Chris Voss, Tahl Raz (Paperback, 2017)

Die with Zero: Getting All You Can from Your Money and Your Life by Bill Perkins (Paperback, 2021)

The Manipulated Man by Esther Vilar (Paperback, 2008)

Code of Practice for In-service Inspection and Testing of Electrical Equipment by The Institution of Engineering and Technology (Paperback, 2020)

The Ethnic Cleansing of Palestine by Ilan Pappe (Paperback, 2007)

Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease and How to Fight It by Benjamin Bikman (Paperback, 2021)

Save on Adult Learning & University

Bold Beans: Beautiful, Brilliant and Exciting Recipes by Amelia Christie-Miller

KS3 Maths Year 8 Targeted Workbook (with answers) by CGP Books (Paperback, 2019)

This Is Why You Dream: What your sleeping brain reveals about your waking life b

The Concise Laws of Human Nature by Robert Greene Paperback, English

Zero to One: Notes on Start Ups, or How to Build the Future by Thiel, Peter The

Why We Get Sick : The Hidden Epidemic at the Root of Most Chronic Disease PB

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