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Bioisosteres in Medicinal Chemistry by Nathan Brown (English) Hardcover Book

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AU $323.46
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Last updated on 18 Jun, 2024 03:12:13 BSTView all revisionsView all revisions

Item specifics

Condition
New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
ISBN-13
9783527330157
Book Title
Bioisosteres in Medicinal Chemistry
ISBN
9783527330157
Subject Area
Chemical Engineering
Publication Name
Bioisosteres in Medicinal Chemistry
Publisher
Wiley-Vch Verlag Gmbh
Subject
Medicine
Publication Year
2012
Type
Textbook
Format
Hardcover
Language
English
Item Height
258 mm
Author
Nathan Brown
Item Weight
628 g
Item Width
170 mm
Number of Pages
256 Pages

About this product

Product Information

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.

Product Identifiers

Publisher
Wiley-Vch Verlag Gmbh
ISBN-13
9783527330157
eBay Product ID (ePID)
114420789

Product Key Features

Number of Pages
256 Pages
Language
English
Publication Name
Bioisosteres in Medicinal Chemistry
Publication Year
2012
Subject
Medicine
Type
Textbook
Author
Nathan Brown
Subject Area
Chemical Engineering
Format
Hardcover

Dimensions

Item Height
258 mm
Item Weight
628 g
Item Width
170 mm

Additional Product Features

Editor
Nathan Brown
Country/Region of Manufacture
Germany
Series Title
Methods & Principles in Medicinal Chemistry

Item description from the seller

Business seller information

The Nile Group Pty Ltd
The Nile
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3029 Truganina, VIC
Australia
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  • AU 82107909133
  • GB 293967539
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