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Chromatin Architecture - 9783319521824

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Last updated on 24 May, 2025 01:08:45 BSTView all revisionsView all revisions

Item specifics

Condition
New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book Title
Chromatin Architecture
ISBN
9783319521824
Publication Name
Chromatin Architecture: Advances from High-Resolution Single Molecule Dna Imaging
Publisher
Springer International Publishing A&G
Subject
Chemistry, Science, Biology
Publication Year
2017
Series
Springer Theses
Type
Textbook
Format
Hardcover
Language
English
Item Height
235 mm
Author
Kirti Prakash
Item Weight
553 g
Item Width
155 mm
Number of Pages
152 Pages

About this product

Product Information

This book sheds new light on the current state of knowledge concerning chromatin organization. Particular emphasis is given to the new imaging potential offered by super-resolution microscopy, which allows DNA imaging with a very high labeling density. From the early work on chromosomes by Walther Flemming in the nineteenth century to recent advances in genomics, the history of chromatin research now spans more than a century. The various milestones, such as the discovery of the double helix structure, the sequencing of the human genome, and the recent description of the genome in 3D space, show that understanding chromatin and chromosome function requires a clear understanding of its structure. Presenting cutting-edge data from super-resolution single molecule microscopy, the book demonstrates that chromatin manifests several levels of folding, from nucleosomes to chromosomes. Chromatin domains emerge as a new fundamental building block of chromatin architecture, with functions possibly related to gene regulation. A detailed description of chromatin folding in the pachytene stage of meiosis serves as a model for exploring this functionality, showing the apparent interplay between structure, function, and epigenetic regulation. Lastly, the book discusses possible new avenues of innovation to describe chromatin's organization and functions. Gathering essential insights on chromatin architecture, the book offers students an introduction to microscopy and its application to chromatin organization, while also providing advanced readers with new ideas for future research.

Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-13
9783319521824
eBay Product ID (ePID)
233318004

Product Key Features

Number of Pages
152 Pages
Publication Name
Chromatin Architecture: Advances from High-Resolution Single Molecule Dna Imaging
Language
English
Subject
Chemistry, Science, Biology
Publication Year
2017
Type
Textbook
Author
Kirti Prakash
Series
Springer Theses
Format
Hardcover

Dimensions

Item Height
235 mm
Item Weight
553 g
Item Width
155 mm

Additional Product Features

Country/Region of Manufacture
Switzerland
Title_Author
Kirti Prakash

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