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Cytoskeleton and Small G Proteins - 9783642636592

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Item specifics

Condition
New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book Title
Cytoskeleton and Small G Proteins
ISBN
9783642636592
Publication Name
Cytoskeleton and Small G Proteins
Publisher
Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG
Subject
Medicine, Chemistry, Biology
Publication Year
2012
Series
Progress in Molecular and Subcellular Biology
Type
Textbook
Format
Paperback
Language
English
Item Height
235 mm
Author
Philippe Jeanteur
Item Weight
391 g
Item Width
155 mm
Number of Pages
234 Pages

About this product

Product Information

Animal cells present an extreme variability in their shapes in relation to their physiological properties. For instance, fibroblastic cells are tightly attached to the extra-cellular matrix and display a flattened, spindle-shaped morphology. Neuronal cells self-organize as a network through a complex branching of dendrites and a long axonal extension. Resting peripheral blood lymphocytes are poorly adhesive and maintain a spherical, smooth shape, while macroph- ages produce many pseudopodal extensions involved in the recognition of foreign molecules. In addition to the variability of the morphology of the cells that constitute different organs, many cell types also modify dynamically their morphology in response to environmental changes, leading to differential cell motility, migration, adhesion, polarity or intercellular contacts. This wide plasticity of cell morphology is promoted and maintained by the cytoskeleton, which is composed of the three interconnected actin micro filaments, tubulin microtubules and intermediate filaments networks, all capable of assembly and disassembly. Over the past few years, the Rho family of Ras-like GTPases emerged as key proteins that mediate extracellular signalling pathways leading to the forma- tion of polymerized actin-containing structures such as ruffles, lamellipodia and filopodia. Since the discovery of the first member RhoA in 1985, 13 mem- bers have so far been characterized in human cells. Most of Rho proteins are highly conserved between species as distant as yeast, slime mold, insects and mammals, which points to their fundamental role in cellular physiology.

Product Identifiers

Publisher
Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG
ISBN-13
9783642636592
eBay Product ID (ePID)
139773657

Product Key Features

Number of Pages
234 Pages
Publication Name
Cytoskeleton and Small G Proteins
Language
English
Subject
Medicine, Chemistry, Biology
Publication Year
2012
Type
Textbook
Author
Philippe Jeanteur
Series
Progress in Molecular and Subcellular Biology
Format
Paperback

Dimensions

Item Height
235 mm
Item Weight
391 g
Item Width
155 mm
Volume
22

Additional Product Features

Editor
Philippe Jeanteur
Country/Region of Manufacture
Germany

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