The technique of microinjection along with viral genetics and molecular biology has proven useful in the correlation of retroviral polynucleotide structure with function. The advantage of this technique is the involvement of living cells where rare activities may be observed and where properties of living cells can be assayed. Future studies involving recombinant DNA molecules and the asso- ciation of proteins with nucleic acids promise to yield additional insight into the nucleotide sequences involved in the expression of viral activities. References Anderson SM, Chen JH (1981) In vitro translation of avian myeloblastosis virus RNA. J Virol 40: 107-117 Berget SM, Moore C, Sharp PA (1977) Spliced segments of the 5' terminus of adenovirus 2 late mRNA. Proc Nat Acad Sci USA 74:3171-3175 Bishop JM (1978) Retroviruses. Annu Rev Biochem 47:35-88 Capecchi MR (1980) High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22:479-488 Chien, Y-H, Junghans RP, Davidson W (1980) Electron microscopic analysis of the structure of RNA tumor virus nucleic acids. In: Stephenson JR (ed) Molecular biology of RNA tumor viruses.
Product Identifiers
Publisher
Springer Berlin / Heidelberg
ISBN-10
3642708129
ISBN-13
9783642708121
eBay Product ID (ePID)
143635179
Product Key Features
Author
H. Koprowski
Publication Name
Retroviruses 4
Format
Trade Paperback
Language
English
Publication Year
2011
Series
Current Topics in Microbiology and Immunology Ser.
Type
Textbook
Number of Pages
VIII, 98 Pages
Dimensions
Item Length
9.6in
Item Height
0.1in
Item Width
6.7in
Item Weight
7.4 Oz
Additional Product Features
Series Volume Number
123
Number of Volumes
1 Vol.
Lc Classification Number
Qr46
Table of Content
Interaction of the Rous Sarcoma Virus Protein pp60src with the Cellular Proteins pp50 and pp90. With 4 Figures.- Microinjection Studies of Retroviral Polynucleotides. With 9 Figures.- The Viral Tyrosine Protein Kinases. With 4 Figures.- Homology Among Oncogenes. With 6 Figures.- Indexed in Current Contents.