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Neuro-Immune Interactions in the Adult Central Nervous System by Oscar González-Pérez (2014, Hardcover)

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Neuro-Immune Interactions in the Adult Central Nervous System, Hardcover by González-pérez, Oscar (EDT), ISBN 1629486469, ISBN-13 9781629486468, Brand New, Free shipping in the US

About this product

Product Identifiers

PublisherNOVA Science Publishers, Incorporated

ISBN-101629486469

ISBN-139781629486468

eBay Product ID (ePID)210287947

Product Key Features

Number of Pages208 Pages

LanguageEnglish

Publication NameNeuro-Immune Interactions in the Adult Central Nervous System

SubjectNeurology

Publication Year2014

TypeTextbook

Subject AreaMedical

AuthorOscar González-Pérez

FormatHardcover

Dimensions

Item Weight17.6 Oz

Item Length9.1 in

Item Width6.1 in

Additional Product Features

Dewey Edition23

IllustratedYes

Dewey Decimal616.80479

Table Of ContentPreface; Influential Effects of Neuronal Regulation of Immune Cells on Brain Diseases; Systemic Inflammatory Reaction & Pathophysiological Alteration in the Brain; Contribution of the Nervous System in the Pathogenesis & Morbidity in Rheumatoid Arthritis; Mesenchymal Stem Cells as Alternative Therapy for Brain Disorders & their Interaction with the Immune System; Neuro-Immune Interactions in Neural Stem Cells of the Postnatal Subventricular Zone; The Role of Cytokines in the Neuroimmunoendocrine Network: Their Participation in Neurotransmission & Reproduction; Neuroimmune Crosstalk in Obesity; The Role of Glia in Stress-Glucocorticoid Effects in the Brain; Immunomodulatory Role of Ensheathing Cells in Spinal Cord Injury; Index.

SynopsisA highly-updated compendium about the interactions between the central nervous system and the immune system that could be very useful for undergraduate students, postgraduate students, academic educators or trainers, basic science researchers and clinical physicians., Increasing evidence indicates that inflammatory cells and immunological cytokines can enter into the brain and modulate a number of biological and cognitive functions. Under physiological conditions, only a few immune cells, such as: macrophages, lymphocytes and dendritic cells can cross the blood-brain barrier and gain access to neural tissue. For many years, these findings supported the notion that the brain was an immunologically privileged organ. To date, increasing evidence strongly challenges this conjecture. In fact, neuroinflammation triggers a significant infiltration of immune cells into the cerebral parenchyma. The infiltration of inflammatory cells is accompanied by the release of a number of cytokines that target neurons, astrocytes and microglia. This interaction between the immune system and the central nervous system modulates many cerebral functions, such as: neural remodelling, synaptic plasticity, neurotransmitter releasing, stress-associated response, cognitive and mental disease progression, and others. The book summarises the latest discoveries, from basic to clinical science, regarding the interactions between the immunological mediators and the neural tissue under physiological and pathological conditions. In this book, it is discussed the influence of immune cells and cytokines in neural-regulated systems. Herein, the readers can find comprehensive descriptions in diverse fields, such as: lipids and obesity, neuronal activity, neurotransmission, stress pathogenesis, rheumatologic diseases, spinal cord injuries, regulation of neural stem cells, neural control of reproduction, and others. To ensure that most of readers obtain clear and complete information, all chapters have been written by prominent experts in their respective fields, who explain these topics with a very accessible language. In summary, this book represents a highly-updated compendium about the interactions between the central nervous system and the immune system that could be very useful for undergraduate students, postgraduate students, academic educators or trainers, basic science researchers and clinical physicians.

LC Classification NumberQP356.47