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About this product
Product Identifiers
PublisherPan Stanford Publishing
ISBN-109814364657
ISBN-139789814364652
eBay Product ID (ePID)112778258
Product Key Features
Number of Pages518 Pages
Publication NameHandbook of Therapeutic Biomarkers in Cancer
LanguageEnglish
Publication Year2013
SubjectPathology, Life Sciences / Cell Biology, Oncology
TypeTextbook
AuthorJanet E. Dancey
Subject AreaScience, Medical
FormatHardcover
Dimensions
Item Height1.3 in
Item Weight30.1 Oz
Item Length9.3 in
Item Width6.1 in
Additional Product Features
Intended AudienceCollege Audience
Dewey Edition23
IllustratedYes
Dewey Decimal616.994075
Table Of ContentOverview: Therapeutic Biomarkers in Cancer. Statistical Considerations in the Development and Evaluation of Therapeutic Biomarkers in Cancer. Role of Biomarkers in Clinical Development of New Cancer Therapies. HER2 as a Prognostic and Predictive Biomarker in Cancer. Hormone Receptors and Endocrine Therapy in Breast Cancer. Predictive Biomarkers for Epidermal Growth Factor Receptor (EGFR) Agents in Non-Small Cell Lung Cancer. Markers of Sensitivity and Resistance to EGFR Inhibitors in Colorectal Cancer. Targeting BCR-ABL for Molecular Therapy of Chronic Myelogenous Leukemia. Gastrointestinal Stromal Tumors (GISTs): From Molecular Pathogenesis to Therapy. PML/RARa Fusion Gene and Response to Retinoic Acid and Arsenic Trioxide Treatment. Dihydropyrimidine Dehydrogenase Deficiency and 5-Fluouracil Toxicity. UGT1A1 Polymorphisms and Mutations Lead to Irinotecan-Induced Toxicity. The 21-Gene Recurrence Score and Benefit of Chemotherapy in Estrogen Receptor-Positive Breast Cancer. MammaPrint for Individualized Recurrence Risk Assessment and Treatment Recommendations for Early-Stage Breast Cancer Patients. BRCA mutation and PARP Inhibitors. EML4-ALK Fusion Gene and Therapy with ALK-targeted Agents in Non-Small Cell Lung Cancer. BRAF-Targeted Therapy in Metastatic Melanoma.
SynopsisIn this volume, a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology.
LC Classification NumberRC270.3.T84
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