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Product Information
In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology.Product Identifiers
PublisherSpringer-Verlag New York Inc.
ISBN-139781461349419
eBay Product ID (ePID)148775416
Product Key Features
Number of Pages202 Pages
Publication NameD N A Topoisomerases in Cancer Therapy: Present and Future
LanguageEnglish
SubjectMedicine, Chemistry
Publication Year2012
TypeTextbook
AuthorToshiwo Andoh
FormatPaperback
Dimensions
Item Height235 mm
Item Weight343 g
Item Width155 mm
Additional Product Features
EditorToshiwo Andoh
Country/Region of ManufactureUnited States
