Pharmaceutical Glycerin mixed with water is always what my dry hands need in winter months. These 6 oz. bottles were readily available at most pharmacies up until a year or so ago, but procurement has recently become elusive for some reason... Pandemic demand? ...That doesn't make sense. Maybe production companies needed to focus on other supplies for the pandemic? I don't know, but after running out right when I needed it, I'm grateful to find another bottle, even at a greatly inflated price. Thankfully, the bottle came intact with it's safety seal still in place.