I originally bought some of these while I was at Crufts Dog Show as a present for a friend with dogs. She reported that her two dogs couldn't get enough of them, that they were amazingly popular and her dogs enjoyed them more than anything else she had ever bought for them. They are small enough to be easily dealt with by the largest (and smallest) of dogs, they are not messy or smelly and the appearance of being 'little bones' is appealing to the human purchasers. Very highly recommended.