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Meselson, Stahl, and the Replication of DNA : A History of "the Most Beautiful Experiment in Biology" by Frederic Lawrence Holmes (2001, Hardcover)
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About this product
Product Identifiers
PublisherYale University Press
ISBN-100300085400
ISBN-139780300085402
eBay Product ID (ePID)1899456
Product Key Features
Number of Pages528 Pages
LanguageEnglish
Publication NameMeselson, Stahl, and the Replication of DNA : A History of "the Most Beautiful Experiment in Biology"
Publication Year2001
SubjectLife Sciences / Molecular Biology, Life Sciences / Genetics & Genomics, History, Life Sciences / Biology
TypeTextbook
Subject AreaScience
AuthorFrederic Lawrence Holmes
FormatHardcover
Dimensions
Item Height1.4 in
Item Weight34.1 Oz
Item Length9.1 in
Item Width6.8 in
Additional Product Features
Intended AudienceScholarly & Professional
LCCN2001-017701
IllustratedYes
SynopsisIn 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a "most beautiful" experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic L. Holmes shows in this masterful account of Meselson and Stahl's quest. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research--its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl's research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community's reception of the experiment, the experiment's influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment.
LC Classification NumberQP624.H654 2001
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