LCCN2014-005466
ReviewsI have used Fain's book for over a decade at Harvard University for my cellular neuroscience class. It offers the perfect mix of rigorous exposition and distilled insights on what makes neurons tick. With clear illustrations (often adapted from original figures from seminal papers in the field), a fluid narrative and careful choice of topics, the book is exceptionally well-suited for a serious introduction to the physiology of neurons. The new edition is a welcome update to an already wonderful original., This book should be essential reading for budding and professional neuroscientists alike. With a new edition, Gordon Fain brings one right up to date on current issues and techniques across a wide range of topics and yet manages to capture the historical source and importance of these ideas as well. No desk should be without access to a copy., I have used Fain's book for over a decade at Harvard University for my cellular neuroscience class. It offers the perfect mix of rigorous exposition and distilled insights on what makes neurons tick. With clear illustrations (often adapted from original figures from seminal papers in the field), a fluid narrative and careful choice of topics, the book is exceptionally well-suited for a serious introduction to the physiology of neurons. The new edition is a welcome update to an already wonderful original. -- Venkatesh N. Murthy, Professor of Molecular and Cellular Biology, Harvard University This book should be essential reading for budding and professional neuroscientists alike. With a new edition, Gordon Fain brings one right up to date on current issues and techniques across a wide range of topics and yet manages to capture the historical source and importance of these ideas as well. No desk should be without access to a copy. -- Jonathan Ashmore, Bernard Katz Professor of Biophysics, University College London Fain explains complex concepts with exquisite clarity. -- David Wallis New Scientist I find Fain's approach remarkably refreshing. -- Jonathan Ashmore Trends in Neuroscience An excellent work. -- D. M. Senseman Choice
IllustratedYes
Table Of ContentContents Preface 1. Introduction Part One: Electrical Properties of Cells and Homeostasis 2. Electrical Properties of Neurons 3. Ion Permeability and Membrane Potentials 4. Ion Pumps and Homeostasis Part Two: Active Propagation of Neural Signals 5. Action Potentials: The Hodgkin-Huxley Experiments 6. The Structure and Function of Voltage-Gated Na+ and K+ Channels 7. The Diversity of Ion Channels Part Three: Synaptic Transmission and Ligand-Gated Channels 8. Presynaptic Mechanisms of Synaptic Transmission (revised by Thomas J. O'Dell) 9. Excitatory Transmission 10. Inhibitory Transmission (revised by Thomas J. O'Dell) Color Illustrations Part Four: Metabotropic Transmission and Neuromodulation 11. Metabotropic Transmission: Receptors and G Proteins 12. Metabotropic Transmission: Effector Molecules 13. Metabotropic Transmission: Calcium 14. Long- Term Potentiation (originally written and newly revised by Thomas J. O'Dell) Part Five: Sensory Transduction 15. Mechanoreceptors 16. Photoreceptors and Olfactory Receptor Neurons Appendix: Symbols Used References Index
SynopsisGordon Fain's Molecular and Cellular Physiology of Neurons: Second Edition is intended for anyone who seeks to understand nerve cell function: undergraduate and graduate students in neuroscience, students of bioengineering and cognitive science, and practicing neuroscientists who want to deepen their knowledge of recent discoveries., Molecular and Cellular Physiology of Neurons, Second Edition is a comprehensive, up-to-date introduction to essential concepts of cellular neuroscience. Emphasizing experimental approaches and recent discoveries, it provides an in-depth look at the structure and function of nerve cells, from protein receptors and synapses to the biochemical processes that drive the mammalian nervous system. Starting with the basics of electrical current flow across cell membranes, Gordon Fain covers voltage gating and receptor activation in the context of channel diversity, excitatory and inhibitory synaptic transmission, neuromodulation, and sensory transduction. Emphasizing long-term processes of synaptic potentiation and depression involved in memory, consciousness, and attention, he demonstrates how cells produce neural signals and regulate signal flow to enhance or impede cell-to-cell communication. Fain also addresses the relation of molecular and cellular mechanisms to evolving theories of neurological disease and addiction. Enhanced by more than two hundred illustrations, Molecular and Cellular Physiology of Neurons, Second Edition is intended for anyone who seeks to understand the fundamentals of nerve cell function, including undergraduate and graduate students in neuroscience, students of bioengineering and cognitive science, and practicing neuroscientists who want to deepen their knowledge of recent discoveries in molecular and cellular neurophysiology., Molecular and Cellular Physiology of Neurons: Second Edition is a comprehensive, up-to-date introduction to essential concepts of cellular neuroscience. Emphasizing experimental approaches and recent discoveries, it provides an in-depth look at the structure and function of nerve cells, from protein receptors and synapses to the biochemical processes that drive the mammalian nervous system. Starting with the basics of electrical current flow across cell membranes, Gordon Fain covers voltage gating and receptor activation in the context of channel diversity, excitatory and inhibitory synaptic transmission, neuromodulation, and sensory transduction. Emphasizing long-term processes of synaptic potentiation and depression involved in memory, consciousness, and attention, he demonstrates how cells produce neural signals and regulate signal flow to enhance or impede cell-to-cell communication. Fain also addresses the relation of molecular and cellular mechanisms to evolving theories of neurological disease and addiction. Enhanced by more than two hundred illustrations, Molecular and Cellular Physiology of Neurons: Second Edition is intended for anyone who seeks to understand the fundamentals of nerve cell function, including undergraduate and graduate students in neuroscience, students of bioengineering and cognitive science, and practicing neuroscientists who want to deepen their knowledge of recent discoveries in molecular and cellular neurophysiology.
LC Classification NumberQP363