Picture 1 of 1

Stock photo

p53 Suppressor Gene - 9783662222775 - Picture 1 of 1

p53 Suppressor Gene by Tapas Mukhopadhyay, Steven A. Maxwell, Jack A. Roth (Paperback, 2014)

BOOKS etc. (533093)

99.5% positive Feedback

Price:

£73.21

Free postage

Estimated delivery Thu, 3 Jul - Wed, 9 Jul

Returns:

60 days return. Buyer pays for return postage. If you use an eBay delivery label, it will be deducted from your refund amount.

Condition:

New

ISBN-13: 9783662222775, 978-3662222775. This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes.

About this product

Product Information

This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. The activity of p53 is regulated by phosphorylation and other transcription factors. Replacement of the p53 function or restoration of the p53 biochemical pathway is a focus of gene therapy.