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Fundamentals of Clinical Trials by Lawrence M. Friedman, Christopher B. Granger, Curt D. Furberg, David M. Reboussin, David L. DeMets (Hardcover, 2015)

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This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing and international trials. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful.

Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-13
9783319185385
eBay Product ID (ePID)
213549588

Product Key Features

Author
Lawrence M. Friedman, Christopher B. Granger, Curt D. Furberg, David M. Reboussin, David L. Demets
Publication Name
Fundamentals of Clinical Trials
Format
Hardcover
Language
English
Subject
Medicine, Mathematics, Healthcare System
Publication Year
2015
Type
Textbook
Number of Pages
550 Pages

Dimensions

Item Height
235mm
Item Width
155mm

Additional Product Features

Title_Author
Lawrence M. Friedman, Curt D. Furberg, Christopher B. Granger, David M. Reboussin, David L. Demets
Country/Region of Manufacture
Switzerland

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Picture 1 of 2

Fundamentals of Clinical Trials by Lawrence M. Friedman, Christopher B. Granger, Curt D. Furberg, David M. Reboussin, David L. DeMets (Hardcover, 2015)

All listings for this product

item 1 Fundamentals of Clinical Trials by Lawrence M. Friedman, Christopher B. Granger,

item 2 Fundamentals of Clinical Trials by Lawrence M. Friedman, Christopher B....

item 3 Fundamentals of Clinical Trials - 9783319185385

item 4 Fundamentals of Clinical Trials, Hardcover by Friedman, Like New Used, Free P...

item 5 Fundamentals of Clinical Trials by Christopher B. Granger NEW Hardback

item 6 Fundamentals of Clinical Trials. Friedman, Furberg, DeMets, **

item 7 Fundamentals of Clinical Trials, Christopher B. Gr

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best-selling in Adult Learning & University

Secrets Of Mental Math: The Mathemagician's Guide to Lightening Calculation and Amazing Maths Tricks by Arthur Benjamin, Michael Shermer (Paperback, 2006)

Happy Odyssey by Adrian Carton de Wiart (Paperback, 2007)

Die with Zero: Getting All You Can from Your Money and Your Life by Bill Perkins (Paperback, 2021)

Code of Practice for In-service Inspection and Testing of Electrical Equipment by The Institution of Engineering and Technology (Paperback, 2020)

Planet Ponzi by Mitch Feierstein (Paperback, 2012)

Becoming Bulletproof: Life Lessons from a Secret Service Agent by Evy Poumpouras (Paperback, 2020)

The Ethnic Cleansing of Palestine by Ilan Pappe (Paperback, 2007)

Save on Adult Learning & University

Health safety and environment test for operatives and specialists 2019 GT100...

The Invisible Rainbow A History of Electricity and Life by Arthur Firstenberg UK

Thinking in Systems International Bestseller, Donella Meadows, Paperback free sh

Diazepam What No One Will Tell You About Pocket Pharmacy

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