Reviews'This book has it all - science and technology, history, ethics, law, and interesting stories of genealogy. It is classic Krimsky - a truly scholarly endeavor made incredibly approachable. Krimsky goes into sufficient depth to empower the reader with the background necessary to appreciate and understand DNA ancestry fully. The book is comprehensive, describing the key discoveries leading to the modern science of ancestry, including the history and development of the multiple generations of technologies used to achieve the resolution of understanding we have today. Applications of the technology's uses and misuses are covered, as well as privacy and ethical considerations. Krimsky is a terrific storyteller of individual cases, where people found out they weren't who they thought they were. He remains in the background throughout as a balanced and unbiased observer. A most interesting and timely book that will inform, entertain, and empower the millions who have had or are considering a consumer DNA test.' David R. Walt, Harvard Medical Schoolid R. Walt, Harvard Medical Schoolid R. Walt, Harvard Medical Schoolid R. Walt, Harvard Medical School, 'Sheldon's book represents a much needed historical, technical, and ethical treatment of this rapidly evolving and growing industry. It tackles a complex topic that many are fascinated by but few have the educational background to appreciate un-shepherded fully, and does so in a way that is accessible and easy to internalize by the very lay readers who have literally built the entire industry with their demand. His book is not only timely, but way, way overdue ... this book is in my view instrumental for anyone considering a genetic ancestry test. If you are a lay consumer of genetic ancestry testing products, it has my highest recommendation for you.' Tony N. Frudakis, Ph.D., Forensic Scientist, Albuquerque Police Department DNA Laboratory, and Founder DNAPrint Genomics, Inc. (1999), 'Understanding DNA Ancestry introduces readers to the vast panoply of complications that can face those who are interested in the sources of their ancestors. Such readers may be surprised that results from different genetic ancestry companies can vary in their conclusions about the results. Test-takers may sometimes confront unexpected surprises that they had never known about co-existing family members, or discover that an assumed relationship may not be genetically based. They will also learn that some ancestry companies help the FBI in identifying criminals using those companies' DNA sequencing collections. Furthermore, eager readers may realize that they are learning more than they knew about genetics. Entering these new studies raises questions about whether supposed classical races of peoples have a genetic basis at all. Professor Krimsky has a long career in preparing detailed collections that have been important to science.' Jonathan Beckwith, Professor Emeritus, Harvard Medical School, Department of Microbiology (and a geneticist) Microbiology (and a geneticist) Microbiology (and a geneticist) Microbiology (and a geneticist)
Dewey Edition23
Table Of Content1. Introduction; 2. The business of DNA ancestry; 3. Geographical origins and movements of early human populations; 4. The science behind DNA ancestry testing; 5. Ancestry informative markers; 6. Ancestry DNA population reference panels; 7. Comparing a donor's DNA to reference panel populations; 8. Probing your DNA; 9. Forensic applications of ancestry DNA results; 10. Privacy, personal identity and legal issues; 11. Discovering unknown, missing or mistaken relatives; 12. Accuracy, consistency and validation of DNA ancestry tests; 13. Conclusion.
Edition DescriptionNew Edition
Intended AudienceTrade
SynopsisAn accessible and engaging introduction to how DNA ancestry tests work and what they can be used for, as well as the ethical and privacy concerns surrounding their use. The book portrays a realistic view of the art and science behind genetic genealogy testing for the general reader., DNA ancestry companies generate revenues in the region of $1bn a year, and the company 23andMe is said to have sold 10 million DNA ancestry kits to date. Although evidently popular, the science behind how DNA ancestry tests work is mystifying and difficult for the general public to interpret and understand. In this accessible and engaging book, Sheldon Krimsky, a leading researcher, investigates the methods that different companies use for DNA ancestry testing. He also discusses what the tests are used for, from their application in criminal investigations to discovering missing relatives. With a lack of transparency from companies in sharing their data, absent validation of methods by independent scientists, and currently no agreed-upon standards of accuracy, this book also examines the ethical issues behind genetic genealogy testing, including concerns surrounding data privacy and security. It demystifies the art and science of DNA ancestry testing for the general reader.